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Cost-effectiveness of the psycho-educational blended (group and online) intervention HypoAware compared with usual care for people with Type 1 and insulin-treated Type 2 diabetes with problematic hypoglycaemia: analyses of a cluster-randomized controlled trial

Aims To evaluate the cost-effectiveness of HypoAware, a blended (group and online) psycho-educational intervention based on the evidence-based Blood Glucose Awareness Training, in comparison with usual care in people with Type 1 and Type 2 diabetes with a high risk of severe hypoglycaemia. Methods We performed an economic evaluation, from a societal and healthcare perspective, that used data from a 6-month, multicentre, cluster-randomized controlled trial (n=137). Results The proportion of p...


Family behaviours that have an impact on the self-management activities of adults living with Type 2 diabetes: a systematic review and meta-synthesis

Aims To identify family behaviours that adults with Type 2 diabetes’ perceive as having an impact on their diabetes self-management. Background Research suggests that adults with Type 2 diabetes perceive that family members have an important impact on their self-management; however, it is unclear which family behaviours are perceived to influence self-management practices. Methods This meta-synthesis identified and synthesized qualitative studies from the databases EMBASE, Medline and CINAHL...


History of mood or anxiety disorders and risk of gestational diabetes mellitus in a population-based cohort

Aim To examine the association between mood and anxiety disorders and the development of gestational diabetes mellitus in a retrospective population-based cohort study. Methods Clinical data from a provincial perinatal health registry were linked to physician claims, hospitalization records and emergency visits to identify any diagnoses of mood or anxiety disorders in the 2 years prior to pregnancy and a subsequent diagnosis of gestational diabetes during pregnancy. The study population includ...


Route to improving Type 1 diabetes mellitus glycaemic outcomes: real-world evidence taken from the National Diabetes Audit

Aim To use general practice-level data for England, available through the National Diabetes Audit, and primary care prescribing data to identify prescription treatment factors associated with variations in achieved glucose control (HbA1c). Methods General practice-level National Diabetes Audit data on Type 1 diabetes, including details of population characteristics, services, proportion of people achieving target glycaemic control [HbA1c 58 mmol/mol (7.5%)] and proportion of people at high gly...


Intrapartum glycaemic control and neonatal hypoglycaemia in pregnancies complicated by diabetes mellitus: a systematic review

Aims To examine whether, in neonates of mothers with Type 1, Type 2 and gestational diabetes mellitus, in-target intrapartum glycaemic control was associated with a lower risk of neonatal hypoglycaemia compared with out-of-target glycaemic control. Methods We searched PubMed and EMBASE for all available publications, regardless of year, based on a published protocol (PROSPERO CRD42016052439). Studies were excluded if they did not report original data or were animal studies. Data were extracted...


Route to improving Type 1 diabetes mellitus glycaemic outcomes: real-world evidence taken from the National Diabetes Audit

The National Diabetes Audit (NDA) has helped to highlight the disparity in glycaemic outcomes between those with Type 1 and those with Type 2 diabetes. Whilst ~70% of those with Type 2 diabetes achieve an HbA1c concentration <58 mmol/mol (7.5%), only 30% of those with Type 1 diabetes do so. Heald et al. [1] have used the data from the NDA to determine whether improved uptake of technology, particularly insulin pump therapy, might improve glycaemic outcomes. This article is protected by copyright...


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