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Mediation and modification of genetic susceptibility to obesity by eating behaviors [Nutritional status, dietary intake, and body composition]

pbBackground:/b Many genetic variants show highly robust associations with body mass index (BMI). However, the mechanisms through which genetic susceptibility to obesity operates are not well understood. Potentially modifiable mec...


Dynamics of intrapericardial and extrapericardial fat tissues during long-term, dietary-induced, moderate weight loss [Nutritional status, dietary intake, and body composition]

pbBackground:/b In view of evidence linking pericardial fat accumulation with increased cardiovascular disease risk, strategies to reduce its burden are needed. Data comparing the effects of specific long-term dietary intervention...


Association of TCN2 rs1801198 c.776G>C polymorphism with markers of one-carbon metabolism and related diseases: a systematic review and meta-analysis of genetic association studies [Gene-nutrient interactions]

pbBackground:/b Vitamin B-12 (cobalamin) deficiency may produce severe neurologic and hematologic manifestations. Approximately 20–25% of circulating cobalamin binds to transcobalamin 2 (TCN2), which is referred to as active...


Soya, maize, and sorghum-based ready-to-use therapeutic food with amino acid is as efficacious as the standard milk and peanut paste-based formulation for the treatment of severe acute malnutrition in children: A noninferiority individually randomized controlled efficacy clinical trial in Malawi [Nutritional epidemiology and public health]

pbBackground:/b Development of more cost-effective ready-to-use therapeutic food (RUTF) is a global public health priority. To date, previous lower-cost recipes have been less effective than the standard peanut and milk (PM)&ndash...


Temporal eating patterns: associations with nutrient intakes, diet quality, and measures of adiposity [Nutritional epidemiology and public health]

pbBackground:/b Some evidence suggests that higher energy intake (EI) later in the day is associated with poor diet quality and obesity. However, EI at one eating occasion (EO) is also dependent on EI at surrounding EOs. Studies t...


Fecal concentrations of bacterially derived vitamin K forms are associated with gut microbiota composition but not plasma or fecal cytokine concentrations in healthy adults [Vitamins, minerals, and phytochemicals]

pbBackground:/b Emerging evidence suggests novel roles for bacterially derived vitamin K forms known as menaquinones in health and disease, which may be attributable in part to anti-inflammatory effects. However, the relevance of ...


Modeling the dose effects of soybean oil in salad dressing on carotenoid and fat-soluble vitamin bioavailability in salad vegetables [Vitamins, minerals, and phytochemicals]

pbBackground:/b Previously, we showed that vegetable oil is necessary for carotenoid absorption from salad vegetables. Research is needed to better define the dose effect and its interindividual variation for carotenoids and fat-s...